Social adversity

Exposure

6 papers5 findings

  • 2 independent labs in 2 countries
  • Funders: National Institute on Aging and 4 more
  • Animals2

Outcomes

1

Physical function

downin dogs1

1 study
  1. Social adversity impairs physical function in dogs.

    “Factors capturing financial and household adversity were associated with poorer health and lower physical mobility in companion dogs”

    Animalsn = 21,410

    Social determinants of health and disease in companion dogs: a cohort study from the Dog Aging Project

    Evolution, medicine, and public healthMay 13, 2023

Associations

3

Mortality

upin reviews2

2 studies
  1. Social adversity raises the risk of mortality.

    “Social adversity can increase the age-associated risk of disease and death”

    Review

    The biology of aging in a social world: Insights from free-ranging rhesus macaques

    Neuroscience and biobehavioral reviewsOct 11, 2023

  2. Social adversity raises the risk of mortality.

    “Social adversity can increase the age-associated risk of disease and death”

    Review

    The biology of aging in a social world:insights from free-ranging rhesus macaques

    bioRxiv : the preprint server for biologyJan 29, 2023Preprint

CD20+/CD3+ ratio

downin rhesus monkeys1

1 study
  1. Social adversity is associated with CD20+/CD3+ ratio in rhesus monkeys.

    “High-status males had higher CD20 + /CD3 + ratios than low-status males.”

    Animalsin malesmales

    Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques

    GeroScienceOct 18, 2023

More on CD20+/CD3+ ratio

CD3+/CD8+ cytotoxic T cells

upin rhesus monkeys1

1 study
  1. Social adversity is associated with CD3+/CD8+ cytotoxic T cells in rhesus monkeys.

    “low-status females had higher proportions of cytotoxic T cells than high-status females”

    Animalsin femalesfemales

    Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques

    GeroScienceOct 18, 2023

More on CD3+/CD8+ cytotoxic T cells

Funding

2 grants since 2021

National Institute on AgingUS$5.3m

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 months