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Sit to stand challenge

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Human trial1

Outcomes

2

30-second chair stand test performance

upin humans1

1 study

  1. Sit to stand challenge improves 30-second chair stand test performance in humans (+2.6±4.1 repetitions).

    “were able to complete an average of 2.6±4.1 more sit to stands during the 30 Second Chair Stand Test after four weeks”

    Human trial4 weeksn = 22

    MONTH-LONG FITNESS CHALLENGES IMPROVE ENDURANCE AND STRENGTH FOR VETERANS PARTICIPATING IN GEROFIT

    GSA 2024 abstract31 Dec 2024

Five Time Sit to Stand time

upin humans1

1 study

  1. Sit to stand challenge improves five Time Sit to Stand time in humans (-1.3±2.3 seconds).

    “decreased their Five Time Sit to Stand times by 1.3±2.3 seconds”

    Human trial4 weeksn = 22

    MONTH-LONG FITNESS CHALLENGES IMPROVE ENDURANCE AND STRENGTH FOR VETERANS PARTICIPATING IN GEROFIT

    GSA 2024 abstract31 Dec 2024

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