Selective ablation of P16-LINEAGE hepatocytes
1 paper1 finding
- 1 lab in 1 country
- Funders: Cancer Research Institute and others
- Animals1
Outcomes
1Hepatic steatosis
downin mice1
1 study
Hepatic steatosis
downin mice1
Selective ablation of P16-LINEAGE hepatocytes decrease hepatic steatosis in mice (~50% reduction (P < 0.0001)).
“selective ablation of p16-Lin(+) hepatocytes reduced hepatic lipid accumulation by approximately 50% (P < 0.0001)”
Animalsin diet-induced MASH modelliver
Selective ablation of p16Ink4a-lineage hepatocytes attenuates hepatic steatosis in diet-induced MASH
Biochemical and biophysical research communications5 Aug 2026
Latest
1 in 12 monthsBiochemical and Biophysical Research Communications
Selective ablation of p16Ink4a-lineage hepatocytes attenuates hepatic steatosis in diet-induced MASH
Experiments in miceCDKN2A