Screening colonoscopy
Intervention1 paper5 findings
- Humans1
Outcomes
1Mortality
no changein humans1HR 1.01Low certainty
1 study
Mortality
no changein humans1HR 1.01Low certainty
Screening colonoscopy has no effect on mortality in humans (HR 1.01, 95% CI 0.97–1.05).
HumansColorectal cancer screening encounter; propensity-matched comparison5 years
Colonoscopy linked to more cancer detection in older adults · JGH open : an open access journal of gastroenterology and hepatology · 4 Oct 2026
Associations
4Gastrointestinal bleeding
downin humans1HR 0.9Low certainty
1 study
Gastrointestinal bleeding
downin humans1HR 0.9Low certainty
Screening colonoscopy is associated with gastrointestinal bleeding in humans (HR 0.90, 95% CI 0.84–0.97).
HumansColorectal cancer screening encounter; propensity-matched comparison1 year
Colonoscopy linked to more cancer detection in older adults · JGH open : an open access journal of gastroenterology and hepatology · 4 Oct 2026
Perforation
upin humans1HR 1.29Low certainty
1 study
Perforation
upin humans1HR 1.29Low certainty
Screening colonoscopy is associated with perforation in humans (HR 1.29, 95% CI 1.02–1.63).
HumansColorectal cancer screening encounter; propensity-matched comparison5 years
Colonoscopy linked to more cancer detection in older adults · JGH open : an open access journal of gastroenterology and hepatology · 4 Oct 2026
Colorectal cancer detection
upin humans1HR 1.78Low certainty
1 study
Colorectal cancer detection
upin humans1HR 1.78Low certainty
Screening colonoscopy is associated with colorectal cancer detection in humans (HR 1.78, 95% CI 1.59–1.98).
HumansColorectal cancer screening encounter; propensity-matched comparison5 years
Colonoscopy linked to more cancer detection in older adults · JGH open : an open access journal of gastroenterology and hepatology · 4 Oct 2026
Polyp detection
upin humans1HR 1.88Low certainty
1 study
Polyp detection
upin humans1HR 1.88Low certainty
Screening colonoscopy is associated with polyp detection in humans (HR 1.88, 95% CI 1.82–1.95).
HumansColorectal cancer screening encounter; propensity-matched comparison5 years
Colonoscopy linked to more cancer detection in older adults · JGH open : an open access journal of gastroenterology and hepatology · 4 Oct 2026
Latest
1Colonoscopy linked to more cancer detection in older adults
Five-year cancer detection was higher with colonoscopy than with no early colonoscopy: the hazard ratio, comparing event rates over time, was 1.78…Five-year cancer detection was higher with colonoscopy than with no early colonoscopy: the hazard ratio, comparing event rates over time, was 1.78; overall mortality was unchanged.