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Prevention of yolk transfer into oocytes

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institute on Aging and 1 more
  • Model organisms1

Outcomes

1

Lifespan

upin worms1

1 study

  1. Prevention of yolk transfer into oocytes extend lifespan in worms.

    “prevention of yolk transfer into the oocytes largely restore fat storage and partially rescue lifespan in the nhr-49 mutants.”

    Model organismsin nhr-49 mutants

    A somatic checkpoint through NHR-49/HNF4α governs reproductive investment and longevity in C. elegans

    Research squareSep 3, 2025Preprint

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