Polypeptide pineal extract
- 1 lab in 1 country
- Animals1
Outcomes
5Mean age of tumour detection
upin rats1
1 study
Mean age of tumour detection
upin rats1
Polypeptide pineal extract increases mean age of tumour detection in rats (811 and 868 days in experimental groups versus 697 days in controls).
“the mean age of tumour detection in the control group was 697 days and in experimental groups it was 811 and 868 days, respectively.”
Animalscompared with controlschronic treatmentfemales
Increase in lifespan of rats following polypeptide pineal extract treatment
Experimentelle Pathologie1 Jan 1979
Neoplasm incidence
no changein rats1
1 study
Neoplasm incidence
no changein rats1
Polypeptide pineal extract has no effect on neoplasm incidence in rats.
“chronic treatment with PPE did not affect the rate of neoplasm incidence”
Animalschronic treatmentfemales
Increase in lifespan of rats following polypeptide pineal extract treatment
Experimentelle Pathologie1 Jan 1979
Gestation and delivery
upin rats1
1 study
Gestation and delivery
upin rats1
Polypeptide pineal extract induces gestation and delivery in rats (4 of 16 animals developed gestation and delivered).
“a second mating period resulted in gestation development in four out of 16 animals and deliveries, accordingly.”
Animalssterility checked by a two-week mating before treatment; second mating after PPEfemalesn = 16
Increase in lifespan of rats following polypeptide pineal extract treatment
Experimentelle Pathologie1 Jan 1979
Persistent disturbances in estral function
downin rats1
1 study
Persistent disturbances in estral function
downin rats1
Polypeptide pineal extract decreases persistent disturbances in estral function in rats (7% of experimental animals versus 38% of controls).
“38% of control rats exhibited persistent disturbances in estral function (constant estrus or repeated pseudogestations), whereas these disorders were observed in 7% of experimental animals only.”
Animalscompared with controlsfemales
Increase in lifespan of rats following polypeptide pineal extract treatment
Experimentelle Pathologie1 Jan 1979
Lifespan
upin rats1
1 study
Lifespan
upin rats1
Polypeptide pineal extract extends lifespan in rats (+10% and +25% at 0.1 and 0.5 mg per animal daily, respectively).
“increased their lifespan by 10 and 25%, respectively, as compared with controls.”
Animalscompared with controlspolypeptide pineal extract0.1 or 0.5 mg per animal daily20 monthsfemales
Increase in lifespan of rats following polypeptide pineal extract treatment
Experimentelle Pathologie1 Jan 1979