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Polα inhibitor

Intervention

1 paper studies it1 finding

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development and 4 more
  • Model organisms1

Outcomes

1

cellular reprogramming

upin human cells1

1 study

  1. Polα inhibitor increases cellular reprogramming in human cells.

    “fine tuning of an inhibitor to modulate Polα activity significantly enhances the efficiency of reprogramming human embryonic fibroblasts into induced pluripotent cells.”

    Cellsfibroblasts

    Modulating DNA Polα Enhances Cell Reprogramming Across Species

    bioRxiv : the preprint server for biologyPreprint

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