Pharmacogenetic return of results

Intervention

1 paper studies it2 findings

1 lab
1 finding against

Human trial1

Outcomes

Systolic blood pressure

downin humans1no changein humans1

1 study

Pharmacogenetic return of results decrease systolic blood pressure in humans (-2.46 mm Hg; 95% CI -4.57 to -0.36).
“In participants with an actionable YEATS4 genotype (N = 867) predicting reduced thiazide efficacy, immediate RoR led to greater SBP reduction at 3 months”
Human trialActionable YEATS4 genotype predicting reduced thiazide efficacy; immediate versus delayed return of results3 monthsn = 867
Immediate gene results did not improve blood pressure overall
Clinical pharmacology and therapeuticsOct 18, 2026
Pharmacogenetic return of results have no effect on systolic blood pressure in humans (-0.3 ± 0.74 mm Hg; 95% CI -1.8 to 1.2).
“Immediate RoR did not improve SBP at 3 months in a broad population of hypertensive adults with controlled and uncontrolled SBP”
Human trialHypertension and self-reported African ancestry; immediate versus delayed return of results3 monthsn = 1,874
Immediate gene results did not improve blood pressure overall
Clinical pharmacology and therapeuticsOct 18, 2026

Latest

1 paper in 12 months

Clinical Pharmacology and Therapeutics2 h

Immediate gene results did not improve blood pressure overall

At three months, the adjusted difference in systolic blood pressure change was minus 0.3 mm Hg for immediate versus delayed genetic results.At three months, the adjusted difference in systolic blood pressure change was minus 0.3 mm Hg for immediate versus delayed genetic results.

Randomized trial · 1,874 peopleInterventions

Paper

Pharmacogenetic return of results

Outcomes

Latest

Immediate gene results did not improve blood pressure overall

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