Perturbation

Exposure

1 paper2 findings

  • 1 lab in 1 country
  • Funders: Fondazione Cariplo and 6 more
  • Cells1

Outcomes

2

Monolayer integrity

downin cells1

1 study
  1. Perturbation impairs monolayer integrity in cells.

    “This intermediate state, experimentally demonstrated in endothelial monolayers, is shown to expose the cellular system to a weakening of cell-to-cell junctions to the detriment of the monolayer integrity.”

    Cellsintermediate disordered metastable state emerging upon perturbation

    Bistability of Dielectrically Anisotropic Nematic Crystals and the Adaptation of Endothelial Collectives to Stress Fields

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Mar 28, 2022

Cell-to-cell junctions

downin cells1

1 study
  1. Perturbation decreases cell-to-cell junctions in cells.

    “reveals the existence of a disordered, metastable state emerging upon system perturbation. This intermediate state, experimentally demonstrated in endothelial monolayers, is shown to expose the cellular system to a weakening of cell-to-cell junctions”

    Cellsintermediate disordered metastable state emerging upon perturbation

    Bistability of Dielectrically Anisotropic Nematic Crystals and the Adaptation of Endothelial Collectives to Stress Fields

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)Mar 28, 2022

Funding

5 grants since 2018

National Institute of Child Health and Human DevelopmentUS$724.5kNational Institute on AgingUS$591.8kNational Institute of Diabetes and Digestive and Kidney DiseasesUS$67.4k

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