Perceived ageism

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Japan Health Promotion and Fitness Foundation and 3 more

Humans1

Outcomes

Happiness

downin humans1

1 study

Perceived ageism decreases happiness in humans (β -0.19, 95% CI -0.27 to -0.11).
“significantly associated with lower happiness (β, -0.19; 95% confidence interval [CI], -0.27 to -0.11)”
Humans3 yearsn = 4,299
Perceived Ageism and Subsequent Health and Well-Being in Older Adults: An Outcome-Wide Longitudinal Analysis From Japan
Journal of the American Geriatrics Society6 Aug 2026

Depressive symptoms

upin humans1

1 study

Perceived ageism increases depressive symptoms in humans (β 0.21, 95% CI 0.14 to 0.29).
“increased depressive symptoms (β, 0.21; 95% CI, 0.14 to 0.29)”
Humans3 yearsn = 4,299
Perceived Ageism and Subsequent Health and Well-Being in Older Adults: An Outcome-Wide Longitudinal Analysis From Japan
Journal of the American Geriatrics Society6 Aug 2026

Associations

Functional disability

upin humans1RR 1.42

1 study

Perceived ageism raises the risk of functional disability in humans (RR 1.42, 95% CI 1.21 to 1.67).
“incident functional disability at any level (risk ratio [RR], 1.42; 95% CI, 1.21 to 1.67)”
Humans3 yearsn = 4,299
Perceived Ageism and Subsequent Health and Well-Being in Older Adults: An Outcome-Wide Longitudinal Analysis From Japan
Journal of the American Geriatrics Society6 Aug 2026

Dementia

upin humans1OR 1.77

1 study

Perceived ageism raises the risk of dementia in humans (OR 1.77, 95% CI 1.31 to 2.39).
“higher risks of incident dementia (odds ratio [OR], 1.77; 95% CI, 1.31 to 2.39)”
Humans3 yearsn = 4,299
Perceived Ageism and Subsequent Health and Well-Being in Older Adults: An Outcome-Wide Longitudinal Analysis From Japan
Journal of the American Geriatrics Society6 Aug 2026

Latest

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Journal of the American Geriatrics Society6 Aug