PACERS

Intervention1 paper4 findings

A human trial in people with hypertension reports that 12 weeks of PACERS lowers systolic and diastolic blood pressure, improves quality of life and increases physical activity.

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab in 1 country

Funders: Association of American Medical Colleges and 2 more

  • Human trial1

Outcomes

4

Quality of life

upin humans1

1 study
  1. PACERS improves quality of life in humans (0.084, 95% CI: 0.022, 0.146, p = 0.008).

    Human trialhypertension12 weeksn = 10

    Development and Preliminary Feasibility Testing of PACERS, a Physical Activity-Centered Intervention for Rural Older Adults With Hypertension · Journal of the American Geriatrics Society · 23 Sep 2026

Physical activity

upin humans1

1 study
  1. PACERS increases physical activity in humans (3612, 95% CI: 855, 6370, p = 0.010).

    Human trialhypertension12 weeksn = 10

    Development and Preliminary Feasibility Testing of PACERS, a Physical Activity-Centered Intervention for Rural Older Adults With Hypertension · Journal of the American Geriatrics Society · 23 Sep 2026

Diastolic blood pressure

downin humans1

1 study
  1. PACERS decreases diastolic blood pressure in humans (-19.14, 95% CI: -31.68, -6.60, p = 0.003).

    Human trialhypertension12 weeksn = 10

    Development and Preliminary Feasibility Testing of PACERS, a Physical Activity-Centered Intervention for Rural Older Adults With Hypertension · Journal of the American Geriatrics Society · 23 Sep 2026

Diastolic blood pressure →

Systolic blood pressure

downin humans1

1 study
  1. PACERS decreases systolic blood pressure in humans (-34.28, 95% CI: -57.77, -10.78, p = 0.004).

    Human trialhypertension12 weeksn = 10

    Development and Preliminary Feasibility Testing of PACERS, a Physical Activity-Centered Intervention for Rural Older Adults With Hypertension · Journal of the American Geriatrics Society · 23 Sep 2026

Systolic blood pressure →

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