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Optimized clinical pathway protocol

Optimized clinical pathway protocol has been studied in 1 paper since 2025: 1 trial in people. The newest paper, Jul 26, 2025: “Effect of an Optimized Clinical Pathway Protocol Including Fascia Iliaca Compartment Block on Delirium and Postoperative Complications in Elderly Hip Fracture Patients”.

Intervention

1 paper studies it3 findingsUpdated

See all 1

“The OCPP intervention significantly reduced the incidence of postoperative delirium from 44% to 29% (a 33% relative reduction; p = 0.017)”
Effect of an Optimized Clinical Pathway Protocol Including Fascia Iliaca Compartment Block on Delirium and Postoperative Complications in Elderly Hip Fracture PatientsJournal of clinical medicine2025doi:10.3390/jcm14155284

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: anesthesia department
  • Human trial1

Studies in people

1 study gave optimized clinical pathway protocol to people and measured what changed.

What did studies of Optimized clinical pathway protocol find?

2

Studies of Optimized clinical pathway protocol measured 2 outcomes; the most studied are postoperative delirium (1 study) and 1-year mortality (1).

Postoperative delirium

downin humans1OR 0.52

1 study

  1. Optimized clinical pathway protocol decreases postoperative delirium in humans (OR 0.52 (95% CI 0.31 to 0.98)).

    “Specifically, the incidence of postoperative delirium was lower in the pathway group (29.3%; 95% CI, 21.0% to 38.0%) than in the control group (43.8%; 95% CI, 35.0% to 52.0%; p = 0.015), with an Odds Ratio of 0.52 (95% CI 0.31 to 0.98).”

    Human trial

    Effect of an Optimized Clinical Pathway Protocol Including Fascia Iliaca Compartment Block on Delirium and Postoperative Complications in Elderly Hip Fracture Patients

    Journal of clinical medicine

  2. Optimized clinical pathway protocol decreases postoperative delirium in humans (44% to 29%, 33% relative reduction, p = 0.017).

    “The OCPP intervention significantly reduced the incidence of postoperative delirium from 44% to 29% (a 33% relative reduction; p = 0.017)”

    Human trialgeriatric hip fracture patients undergoing surgery

    Effect of an Optimized Clinical Pathway Protocol Including Fascia Iliaca Compartment Block on Delirium and Postoperative Complications in Elderly Hip Fracture Patients

    Journal of clinical medicine

More on Postoperative delirium

1-year mortality

no changein humans1

1 study

  1. Optimized clinical pathway protocol has no effect on 1-year mortality in humans.

    “No differences were observed on hospital stay and 1-year mortality.”

    Human trial

    Effect of an Optimized Clinical Pathway Protocol Including Fascia Iliaca Compartment Block on Delirium and Postoperative Complications in Elderly Hip Fracture Patients

    Journal of clinical medicine

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