Advanced Science
Early drug dosing prevents pain-related behavior in mice
Weekly dosing for five months also preserved spinal disc volume and bone structure in mice prone to early spine degeneration.Weekly dosing for five months also preserved spinal disc volume and bone structure in mice prone to early spine degeneration.
Mouse studyInterventions
Who was studiedMale and female mice lacking Sparc, five months
What changedEither drug reduced cold sensitivity compared with Sparc-deficient mice given drug-free liquid
The catchPain was assessed indirectly through behavioral tests