Neutrons

1. Neutrons increase mortality in mice.

   “RSF interpretation using Shapley Additive Explanations revealed a dose response for mortality risk that curved upwards at low doses < 20 cGy, became nearly-linear over 20-150 cGy, and saturated at high doses.”

   Animalsn = 21,308

   Quantifying the effects of neutron dose, dose protraction, age and sex on mouse survival using parametric regression and machine learning on a 21,000-mouse data set

   Scientific reports·9 Dec 2023

1. Neutrons decrease lifespan in mice (-4.2%).

   “Exposure of mice to a dose of 600 Gy of proton beam-generated neutrons, reduced the median life span of the mice by 4.2% (Kaplan-Meier cumulative survival, P=.053).”

   Animalsproton beam-generated neutrons (600 Gy protons to phantom)femalesn = 300

   Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons

   International journal of radiation oncology, biology, physics·1 May 2014

1. Neutrons raise the risk of leukemia in mice.

   “resulted in a statistically significant increase in the background incidence of leukemia”

   Animalsproton dose that exceeds typical course by factor of 10females

   Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons

   International journal of radiation oncology, biology, physics·1 May 2014

More on Leukemia

1. Neutrons raise the risk of solid cancer in mice (RR 1.22).

   “and 1.22 for solid cancers (P=.09).”

   Animalsproton beam-generated neutrons (600 Gy protons to phantom)femalesn = 300

   Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons

   International journal of radiation oncology, biology, physics·1 May 2014

More on Solid cancer

1. Neutrons raise the risk of cancer in mice (RR 1.40).

   “The relative risk of death from cancer in neutron exposed versus control mice was 1.40 for cancer of all types (P=.0006)”

   Animalsproton beam-generated neutrons (600 Gy protons to phantom)femalesn = 300

   Lifetime increased cancer risk in mice following exposure to clinical proton beam-generated neutrons

   International journal of radiation oncology, biology, physics·1 May 2014

More on Cancer