Neoadjuvant chemotherapy
Intervention1 paper2 findings
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.
- Humans1
Outcomes
1Circulatory mortality
no changein humans1
1 study
Circulatory mortality
no changein humans1
Neoadjuvant chemotherapy has no effect on circulatory mortality in humans (csHR 1.092 (95% CI 0.968-1.231)).
Humansfemalesn = 74,233
Circulatory and other-cause mortality after neoadjuvant versus adjuvant chemotherapy in women with stage II-III breast cancer · Biomolecules & biomedicine · 18 Aug 2026
Associations
1Circulatory mortality
no changein humans1
1 study
Circulatory mortality
no changein humans1
Neoadjuvant chemotherapy is associated with circulatory mortality in humans (risk difference -0.05 percentage points (95% CI -0.31 to 0.18)).
Humansfemalesn = 74,233
Circulatory and other-cause mortality after neoadjuvant versus adjuvant chemotherapy in women with stage II-III breast cancer · Biomolecules & biomedicine · 18 Aug 2026