Natural microbiome
1 paper2 findings
- 1 lab in 1 country
- Funder: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Animals1
Outcomes
2Naive T cell replacement rate
no changein mice1
1 study
Naive T cell replacement rate
no changein mice1
Natural microbiome has no effect on naive T cell replacement rate in mice.
“naive T cells rarely divide and are replaced by thymic emigrants at similar rates.”
Animalsin both standard laboratory mice and wildlings
TRECing down the source: naive and memory T cell generation in dirty mice and men
Journal of immunology (Baltimore, Md. : 1950)4 Aug 2026
Memory T cell replacement rate
upin mice1+50% faster
1 study
Memory T cell replacement rate
upin mice1+50% faster
Natural microbiome increases memory T cell replacement rate in mice (about 50% faster).
“The daily replacement rate of memory T cells, on the other hand, is about 50% faster in wildlings than in standard laboratory mice.”
Animalsin wildlings compared to standard laboratory mice
TRECing down the source: naive and memory T cell generation in dirty mice and men
Journal of immunology (Baltimore, Md. : 1950)4 Aug 2026
Latest
1 in 12 monthsJournal of Immunology
TRECing down the source: naive and memory T cell generation in dirty mice and men
Experiments in miceBlood and immune system