AgingResearch.NewsJoin free

N,n-dimethyltryptophan-containing dipeptide

Intervention

1 paper studies it3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Howard Hughes Medical Institute and 5 more
  • Model organisms1

Outcomes

3

Larval development rate

upin worms1

1 study

  1. N,n-dimethyltryptophan-containing dipeptide increases larval development rate in worms.

    “an unusual dipeptide incorporating N,N-dimethyltryptophan, increases food consumption, reduces lifespan, and accelerates the last stage of larval development in hermaphrodites.”

    Model organismshermaphroditess

    Sex-specificity of the C. elegans metabolome

    Nature communicationsJan 19, 2023

Food consumption

upin worms1

1 study

  1. N,n-dimethyltryptophan-containing dipeptide increases food consumption in worms.

    “an unusual dipeptide incorporating N,N-dimethyltryptophan, increases food consumption, reduces lifespan, and accelerates the last stage of larval development in hermaphrodites.”

    Model organismshermaphroditess

    Sex-specificity of the C. elegans metabolome

    Nature communicationsJan 19, 2023

Lifespan

downin worms1

1 study

  1. N,n-dimethyltryptophan-containing dipeptide shortens lifespan in worms.

    “an unusual dipeptide incorporating N,N-dimethyltryptophan, increases food consumption, reduces lifespan, and accelerates the last stage of larval development in hermaphrodites.”

    Model organismshermaphroditess

    Sex-specificity of the C. elegans metabolome

    Nature communicationsJan 19, 2023

Latest

Related