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Muscle stretching

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: American Heart Association and 6 more
  • Human trial1

Outcomes

3

Nitroglycerin-induced dilation

no changein humans1

1 study

  1. Muscle stretching has no effect on nitroglycerin-induced dilation in humans (10.9 ± 1.2 vs. 9.9 ± 0.4%).

    “No difference in nitroglycerin-induced dilation was found between groups (10.9 ± 1.2 vs. 9.9 ± 0.4%, P = 0.48).”

    Human trialin stable symptomatic peripheral artery disease4 weeksn = 13

    Daily Passive Muscle Stretching Improves Flow-Mediated Dilation of Popliteal Artery and 6-minute Walk Test in Elderly Patients with Stable Symptomatic Peripheral Artery Disease

    Cardiovascular revascularization medicine : including molecular interventions10 May 2019

More on Nitroglycerin-induced dilation

Continuous walking distance

upin humans1

1 study

  1. Muscle stretching improves continuous walking distance in humans (304 ± 43 m vs. 182 ± 34 m).

    “6MWT continuous walking distance: 304 ± 43 m vs. 182 ± 34 m; P = 0.0006”

    Human trialin stable symptomatic peripheral artery disease4 weeksn = 13

    Daily Passive Muscle Stretching Improves Flow-Mediated Dilation of Popliteal Artery and 6-minute Walk Test in Elderly Patients with Stable Symptomatic Peripheral Artery Disease

    Cardiovascular revascularization medicine : including molecular interventions10 May 2019

Flow-mediated dilation

upin humans1

1 study

  1. Muscle stretching improves flow-mediated dilation in humans (5.1 ± 0.5% vs. 3.7 ± 0.3%).

    “FMD: 5.1 ± 0.5% vs. 3.7 ± 0.3%, P = 0.005”

    Human trialin stable symptomatic peripheral artery disease4 weeksn = 13

    Daily Passive Muscle Stretching Improves Flow-Mediated Dilation of Popliteal Artery and 6-minute Walk Test in Elderly Patients with Stable Symptomatic Peripheral Artery Disease

    Cardiovascular revascularization medicine : including molecular interventions10 May 2019

More on Flow-mediated dilation

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