Muscle-resident stromal cells
Muscle-resident stromal cells has been studied in 1 paper since 2017: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Dec 18, 2017: “The impact of mechanically stimulated muscle-derived stromal cells on aged skeletal muscle”.
1 paper studies it3 findingsUpdated
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Abbott Nutrition and 6 more
- Animals1
What did studies of Muscle-resident stromal cells find?
3Studies of Muscle-resident stromal cells measured 3 outcomes; the most studied are new neuron and astrocyte counts (1 study), muscle perfusion (1) and maximal muscle force (1).
New neuron and astrocyte counts
upin mice1
1 study
New neuron and astrocyte counts
upin mice1
Muscle-resident stromal cells increase new neuron and astrocyte counts in mice.
“Intramuscular injection of preconditioned mMSCs increased the number of new neurons and astrocytes in the dentate gyrus of the hippocampus compared to both control groups (p<0.05)”
Animalscompared with saline and non-strain control mMSCsmechanically preconditioneddentate gyrus of the hippocampus4×104 cells
The impact of mechanically stimulated muscle-derived stromal cells on aged skeletal muscle
Experimental gerontology
Muscle perfusion
upin mice1
1 study
Muscle perfusion
upin mice1
Muscle-resident stromal cells increase muscle perfusion in mice.
“Peripheral perfusion was significantly increased in muscle at 4wks post-mMSC injection (p<0.05), yet no difference was noted between control and preconditioned mMSCs.”
Animalsnon-strain control or mechanically preconditionedskeletal muscle4×104 cells4 weeks
The impact of mechanically stimulated muscle-derived stromal cells on aged skeletal muscle
Experimental gerontology
Maximal muscle force
no changein mice1
1 study
Maximal muscle force
no changein mice1
Muscle-resident stromal cells have no effect on maximal muscle force in mice.
“No significant changes were observed in muscle weight, myofiber size, maximal force, or satellite cell quantity at 1 or 4wks between groups.”
Animalscompared with saline and non-strain control mMSCsmechanically preconditionedskeletal muscle4×104 cells1 or 4 weeks
The impact of mechanically stimulated muscle-derived stromal cells on aged skeletal muscle
Experimental gerontology