Multivitamin and multimineral supplementation

Multivitamin and multimineral supplementation has been studied in 2 papers since 2007: 1 trial in people, 1 review. The newest paper, Aug 3, 2018: “Effects of Multivitamin and Multimineral Supplementation on Blood Pressure: A Meta-Analysis of 12 Randomized Controlled Trials”.

Intervention

2 papers study it3 findingsUpdated

“For digit span forward there was no evidence of an effect of supplements in all participants or in sub-groups defined by age or risk of deficiency.”
Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: a randomised controlled trialNutrition journal2007doi:10.1186/1475-2891-6-10
  • 2 independent labs in 2 countries
  • Funders: China Postdoctoral Science Foundation and 3 more
  • Human trial1

What did studies of Multivitamin and multimineral supplementation find?

3

Studies of Multivitamin and multimineral supplementation measured 3 outcomes; the most studied are hypertension (1 study), systolic blood pressure (1) and memory (1).

Hypertension

no changein humans1

1 study
  1. Multivitamin and multimineral supplementation has no effect on hypertension in humans.

    “There was no significant effect of MVMS on risk of hypertension in 22,852 subjects with a normal blood pressure at baseline.”

    Reviewin subjects with a normal blood pressure at baselinen = 22,852

    Effects of Multivitamin and Multimineral Supplementation on Blood Pressure: A Meta-Analysis of 12 Randomized Controlled Trials

    Nutrients

More on Hypertension

Systolic blood pressure

downin humans1

1 study
  1. Multivitamin and multimineral supplementation decreases systolic blood pressure in humans (WMD -1.31 mmHg, 95% CI -2.48 to -0.14 mmHg).

    “MVMS had a lowering effect on systolic blood pressure (SBP) and diastolic blood pressure (DBP): the weighted mean difference (WMD) was -1.31 mmHg (95% CI, -2.48 to -0.14 mmHg)”

    Reviewn = 2,011

    Effects of Multivitamin and Multimineral Supplementation on Blood Pressure: A Meta-Analysis of 12 Randomized Controlled Trials

    Nutrients

Memory

no changein humans1

1 study
  1. Multivitamin and multimineral supplementation has no effect on memory in humans.

    “For digit span forward there was no evidence of an effect of supplements in all participants or in sub-groups defined by age or risk of deficiency.”

    Human trialtablet12 monthsn = 910

    Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: a randomised controlled trial

    Nutrition journal

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