Move!+up
Move!+up has been studied in 2 papers since 2023: 2 trials in people; 1 in the past year. The newest paper, Mar 2, 2026: “Enhanced Weight Management Program for Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial”.
2 papers study it5 findingsUpdated
At a glance
The findings reach people, from one lab or study. 2 independent labs in 1 country.
“Adjusted intervention minus control mean weight change was -1.5 lb (95% CI, -5.9 to 2.9; P = .50).”
1 of its findings points the other way.
- 2 independent labs in 1 country
- 1 finding against
- Funders: US Department of Veterans Affairs and 3 more
- Human trial2
Studies in people
2 studies gave move!+up to people and measured what changed.
| What changed | Design | People | Source |
|---|---|---|---|
no change: Has no effect on body weightmean adjusted between-group, intervention minus control, −1.52 lb (95% CI, −5.93 to 2.89 lb) no change: Has no effect on posttraumatic stress disorder | Randomized trial16 weekly sessions | 174 people113 men (65%) and 61 women (35%)mean (SD) age, 55 (13) yearsVeterans receiving PTSD care with a body mass index of 25 or greater and no dementia diagnosis | JAMA network open, Mar 2, 2026 |
down: Decreases body weight up: Improves lower extremity function | Trial13 months | 303 peopleolder adultsOlder adults; overweight or obese | Health promotion practice, Mar 28, 2023 |
What did studies of move!+up find?
4Studies of move!+up measured 4 outcomes; the most studied are body weight (2 studies), posttraumatic stress disorder (1) and body weight (1).
Body weight
no changein humans1downin humans1
2 studies
Body weight
no changein humans1downin humans1
Move!+up showed no clear effect on body weight in humans (PTSD and elevated body mass index) (-1.5 lb (95% CI, -5.9 to 2.9; P = .50)).
“Adjusted intervention minus control mean weight change was -1.5 lb (95% CI, -5.9 to 2.9; P = .50).”
Human trialPTSD and elevated body mass index6 monthsn = 174
JAMA network open
Move!+up decreases body weight in humans (overweight or obese).
“The program was effective for weight loss and lower extremity function in both intervention and maintenance periods (ps < .01)”
Human trialoverweight or obese13 monthsn = 303
Health promotion practice
Posttraumatic stress disorder
no changein humans1
1 study
Posttraumatic stress disorder
no changein humans1
Move!+up showed no clear effect on posttraumatic stress disorder in humans (compared to MOVE!).
“There were no statistically significant differences between MOVE!+UP and MOVE! for secondary or exploratory outcomes in unadjusted and adjusted analyses.”
Human trialcompared to MOVE!16 weekly sessionsn = 174
JAMA network open
Body weight
no changein humans1
1 study
Body weight
no changein humans1
Move!+up showed no clear effect on body weight in humans (compared to MOVE!) (mean adjusted between-group, intervention minus control, −1.52 lb (95% CI, −5.93 to 2.89 lb)).
“In adjusted analyses, there was no statistically significant difference between groups in weight change (mean adjusted between-group, intervention minus control, −1.52 lb; 95% CI, −5.93 to 2.89 lb; P =.50).”
Human trialcompared to MOVE!16 weekly sessionsn = 174
JAMA network open
Lower extremity function
upin humans1
1 study
Lower extremity function
upin humans1
Move!+up improves lower extremity function in humans (overweight or obese).
“The program was effective for weight loss and lower extremity function in both intervention and maintenance periods (ps < .01)”
Human trialoverweight or obese13 monthsn = 303
Health promotion practice