Monosodium urate crystals

1. Monosodium urate crystals induce immune response in humans.

   Reviewvia JNK-JUN and mTOR-HIF-1alpha axes

   Trained immunity in gout: epigenetic and metabolic reprogramming of innate immune memory · Frontiers in immunology · 12 Aug 2026

Immune response →

1. Monosodium urate crystals activate NLRP3 inflammasome in humans.

   Reviewin gout pathogenesis

   Trained immunity in gout: epigenetic and metabolic reprogramming of innate immune memory · Frontiers in immunology · 12 Aug 2026

NLRP3 inflammasome →