Modifiable risk factors

1. Modifiable risk factors decrease cognitive function in humans (p < 0.001).

   “Clinical judgement of cognitive functioning (COGSTAT) scores were inversely correlated with total, past, present RFPs ( p < 0.001)”

   Humans

   Exploring Racial Disparities in Cognitive Decline and Dementia: Analyzing Total, Past, and Present Risk Factors Profiles, Cognition, and Vascular Brain Health Outcomes

   AAIC 2025 abstract·23 Dec 2025

1. Modifiable risk factors are associated with infarcts in humans (p < 0.001).

   “infarcts were significantly associated with total, past, present RFPs in White and Asian participants ( p < 0.001)”

   Humansin White and Asian participants

   Exploring Racial Disparities in Cognitive Decline and Dementia: Analyzing Total, Past, and Present Risk Factors Profiles, Cognition, and Vascular Brain Health Outcomes

   AAIC 2025 abstract·23 Dec 2025

More on Infarcts

1. Modifiable risk factors are associated with white matter hyperintensities in humans (p < 0.001).

   “WMHs were significantly associated with total, past, present RFPs in both White and Black participants ( p < 0.001).”

   Humansin White and Black participants

   Exploring Racial Disparities in Cognitive Decline and Dementia: Analyzing Total, Past, and Present Risk Factors Profiles, Cognition, and Vascular Brain Health Outcomes

   AAIC 2025 abstract·23 Dec 2025

More on White matter hyperintensities