Miricorilant

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Augusta University and 3 more

Animals1

Outcomes

Epidermal thickness

no changein mice1

1 study

Miricorilant has no effect on epidermal thickness in mice.
“None of the antagonists significantly altered proliferation markers, epidermal thickness, or regulators of glucocorticoid activity.”
Animalsskin8 weeksfemales
The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice
International journal of molecular sciences28 Aug 2025

Inflammation

downin mice1

1 study

Miricorilant decreases inflammation in mice.
“downregulated key inflammatory cytokines”
Animalsskin8 weeksfemales
The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice
International journal of molecular sciences28 Aug 2025

Latest

International Journal of Molecular Sciences13 Sep

The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice

Experiments in miceSkin

Paper

Miricorilant

Outcomes

Latest

The Effect of Glucocorticoid and Mineralocorticoid Receptor Antagonists in the Skin of Aged Female Mice

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