Microglial transplantation
1 paper2 findings
- 1 lab in 1 country
- Funders: California Institute for Regenerative Medicine and others
- Animals1
Outcomes
2Cerebral amyloid angiopathy
downin mice1
1 study
Cerebral amyloid angiopathy
downin mice1
Microglial transplantation protects against cerebral amyloid angiopathy in mice.
“These results indicate the protective functions of microglia in reducing CAA, blood-brain barrier dysfunction, and brain calcification.”
Animalsin Alzheimer's disease micebrain
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice
Cell reports14 Jun 2022
Premature lethality
downin mice1
1 study
Premature lethality
downin mice1
Microglial transplantation protects against premature lethality in mice.
“A single injection of wild-type microglia into adult mice repopulates the microglial niche and prevents each of these pathological changes.”
Animalsin Alzheimer's disease micebrain
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice
Cell reports14 Jun 2022
Latest
Cell Reports
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice
Experiments in miceMechanisms