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Micheliolide

Intervention

1 paper studies it4 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 1 more
  • Animals1

Outcomes

4

p38 MAPK signaling

downin mouse cells1

1 study

  1. Micheliolide inhibits p38 MAPK signaling in mouse cells.

    “Micheliolide inhibits osteoclasts formation via inhibiting P38 MAPK signaling pathway”

    Cells

    Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption

    AgingOct 11, 2023

More on p38 MAPK signaling

Osteoclastogenesis

downin mouse cells1

1 study

  1. Micheliolide inhibits osteoclastogenesis in mouse cells.

    “Micheliolide could inhibit osteoclastogenesis in vitro”

    Cells

    Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption

    AgingOct 11, 2023

Bone resorption

downin mice1

1 study

  1. Micheliolide inhibits bone resorption in mice.

    “Micheliolide treatment inhibits excessive osteoclast bone resorption”

    Animalsin estrogen deficiency mice

    Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption

    AgingOct 11, 2023

Bone loss

downin mice1

1 study

  1. Micheliolide protects against bone loss in mice.

    “Micheliolide could protect mice from ovariectomy induced bone loss”

    Animalsovariectomy-induced estrogen deficiency

    Micheliolide prevents estrogen deficiency-induced bone loss via inhibiting osteoclast bone resorption

    AgingOct 11, 2023

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