Low-intensity resistance training with blood flow restriction
Intervention1 paper3 findings
Outcomes
2Cross-linked C-telopeptides of type I collagen
downin humans1Low certainty
1 study
Cross-linked C-telopeptides of type I collagen
downin humans1Low certainty
Low-intensity resistance training with blood flow restriction decreases cross-linked C-telopeptides of type I collagen in humans (MD -0.08 (95% CI -0.13 to -0.03)).
ReviewCompared with high-intensity resistance training; very low certainty of evidence
Effects of blood flow restriction and resistance training on bone health biomarkers and Bone Mineral Density: a Systematic Review and Meta-Analysis · Advances in medical sciences · 6 Oct 2026
Bone-specific alkaline phosphatase
downin humans1Low certainty
1 study
Bone-specific alkaline phosphatase
downin humans1Low certainty
Low-intensity resistance training with blood flow restriction decreases bone-specific alkaline phosphatase in humans (MD -2.72 (95% CI -5.17 to -0.28)).
ReviewCompared with high-intensity resistance training; very low certainty of evidence
Effects of blood flow restriction and resistance training on bone health biomarkers and Bone Mineral Density: a Systematic Review and Meta-Analysis · Advances in medical sciences · 6 Oct 2026
Associations
1Bone mineral density
mixedin humans1Low certainty
1 study
Bone mineral density
mixedin humans1Low certainty
Low-intensity resistance training with blood flow restriction is associated with bone mineral density in humans.
ReviewHigher versus low-intensity resistance training, similar versus high-intensity resistance training, lower versus non-exercise; very low certainty of evidencebone
Effects of blood flow restriction and resistance training on bone health biomarkers and Bone Mineral Density: a Systematic Review and Meta-Analysis · Advances in medical sciences · 6 Oct 2026