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LL-37 gene therapy

LL-37 gene therapy has been studied in 1 paper since 2021: none in people yet, 1 in cells. No study of it in people or animals has been published yet. The newest paper, Jul 5, 2021: “Nonviral Expression of LL-37 in a Human Skin Equivalent to Prevent Infection in Skin Wounds”.

Intervention

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Cells1

What did studies of LL-37 gene therapy find?

1

Studies of LL-37 gene therapy measured 1 outcome; the most studied are antimicrobial activity (1 study).

Antimicrobial activity

upin human cells1

1 study

  1. LL-37 gene therapy increases antimicrobial activity in human cells.

    “HSEs that express elevated levels of LL-37 were shown to possess histological characteristics close to the normal skin and display enhanced antimicrobial activity against S. aureus in vitro.”

    Cellsin vitrotransfected human skin equivalents

    Nonviral Expression of LL-37 in a Human Skin Equivalent to Prevent Infection in Skin Wounds

    Human gene therapy

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