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Liver stem cells

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 1 more
  • Animals1

Outcomes

1

Lifespan

upin mice1

1 study

  1. Liver stem cells extend lifespan in mice.

    “Grafting of ex vivo expanded LSCs in Fah-/- Rag2-/- Il2rg-/- knockout mice, significantly increased life span compared to control group (P < 0.001).”

    Animalsin Fah-/- Rag2-/- Il2rg-/- knockout mice

    A small molecule Hedgehog agonist HhAg1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure

    Translational research : the journal of laboratory and clinical medicine19 Oct 2018

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