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Lifetime adversity

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: National Center for Advancing Translational Sciences and 5 more
  • Humans1

Associations

1

Emotion regulation difficulties

upin humans1

1 study

  1. Lifetime adversity is associated with emotion regulation difficulties in humans.

    “difficulty in regulating emotions being associated with greater lifetime adversity throughout the sample.”

    HumansHealthy volunteers; stronger association in Black participants, particularly for assaultive trauman = 459

    Race-related differences in protective effects of emotion regulation against GrimAge acceleration are driven by assaultive trauma

    Psychological trauma : theory, research, practice and policy14 Apr 2025

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