Ionized poly

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • 2 of 2 findings with company ties
  • Animals1

Outcomes

2

Chemosensitivity

upin mice1

1 study
  1. Ionized poly improves chemosensitivity in mice.

    “chemosensitivity was increased with protein replacement therapy”

    Animalsprotein replacement therapy with p53 mRNA delivered to lung via iPβAE

    Backbone-Ionized Polymers for Quantitatively Guided Extra-Hepatic mRNA Expression via Differential Local Structural Rearrangement

    Journal of the American Chemical Society12 Aug 2026

Lifespan

upin mice1

1 study
  1. Ionized poly extends lifespan in mice (20 times).

    “The lifespan of mice was extended by 20 times with vaccine immunotherapy”

    Animalsvaccine immunotherapy with antigen mRNA (OVA/MUC1) delivered via iPβAE

    Backbone-Ionized Polymers for Quantitatively Guided Extra-Hepatic mRNA Expression via Differential Local Structural Rearrangement

    Journal of the American Chemical Society12 Aug 2026

Latest

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