Institutionalization

1. Institutionalization has no effect on frailty in humans (p = 0.674).

   “No significant differences were found in frailty levels between the groups (p = 0.674).”

   Humanscommunity-dwelling vs institutionalizedn = 77

   Comparison of Frailty and Autonomy Levels in Older Adults According to Place of Residence

   Healthcare (Basel, Switzerland)·12 Mar 2026

1. Institutionalization decreases autonomy in humans (94.21 ± 10.81 vs 75.53 ± 23.21, p < 0.001).

   “Older adults in the community showed significantly higher levels of autonomy (94.21 ± 10.81) compared to those who were institutionalized (75.53 ± 23.21; p < 0.001).”

   Humanscommunity-dwelling vs institutionalizedn = 77

   Comparison of Frailty and Autonomy Levels in Older Adults According to Place of Residence

   Healthcare (Basel, Switzerland)·12 Mar 2026

1. Institutionalization increases melatonin in humans.

   “Blood cortisol (p = 0.0309) and melatonin (p = 0.0407) were also elevated.”

   Humansinstitutionalized individuals vs individuals living with family members

   Hormonal and Cytokine Imbalances Promote a Proinflammatory Profile in Institutionalized Elderly

   Brain sciences·5 Dec 2025

More on Melatonin

1. Institutionalization increases cortisol in humans.

   “Blood cortisol (p = 0.0309) and melatonin (p = 0.0407) were also elevated.”

   Humansinstitutionalized individuals vs individuals living with family members

   Hormonal and Cytokine Imbalances Promote a Proinflammatory Profile in Institutionalized Elderly

   Brain sciences·5 Dec 2025

More on Cortisol

1. Institutionalization increases IL-6 in humans.

   “Institutionalized individuals showed higher IL-6 (p = 0.0261) and IFN-γ (p = 0.0065)”

   Humansinstitutionalized individuals vs individuals living with family members

   Hormonal and Cytokine Imbalances Promote a Proinflammatory Profile in Institutionalized Elderly

   Brain sciences·5 Dec 2025

More on IL-6

1. Institutionalization is associated with depression in humans.

   “Institutionalized participants reported significantly higher depression scores, with mean scores at the commonly used GDS-15 screening threshold.”

   Humansinstitutionalized vs community-dwellingn = 190

   Depression, anxiety, anger, and loneliness in older adults: comparing residential contexts and examining the role of loneliness

   BMC geriatrics·15 May 2026

More on Depression

1. Institutionalization is associated with physical activity in humans (∆% = - 64.3%, p = 0.027X).

   “lower physical activity (∆% = - 64.3%, p = 0.027X)”

   Humans

   Fatores de Risco Cardiovascular de Pessoas Idosas em Situação de Acolhimento Doméstico ou Institucional

   Preprint·2 Apr 2025

1. Institutionalization is associated with stroke in humans (∆% = 3.4%, p = 0.002).

   “Institutionalized elderly individuals had a higher prevalence of cardiovascular diseases, especially diabetes (∆% = 47.6%, p = 0.015) and stroke (∆% = 3.4%, p = 0.002)”

   Humans

   Fatores de Risco Cardiovascular de Pessoas Idosas em Situação de Acolhimento Doméstico ou Institucional

   Preprint·2 Apr 2025

More on Stroke

1. Institutionalization is associated with diabetes in humans (∆% = 47.6%, p = 0.015).

   “Institutionalized elderly individuals had a higher prevalence of cardiovascular diseases, especially diabetes (∆% = 47.6%, p = 0.015)”

   Humans

   Fatores de Risco Cardiovascular de Pessoas Idosas em Situação de Acolhimento Doméstico ou Institucional

   Preprint·2 Apr 2025

More on Diabetes