Inhbe sirna
1 paper3 findings
- 1 lab
- Animals1
Outcomes
3INHBE mRNA
downin mice1−94%
1 study
INHBE mRNA
downin mice1−94%
Inhbe sirna decreases INHBE mRNA in mice (-93.8%).
“INHBE mRNA levels decreased by 93.8%.”
Animalsdiet-induced obesity9 mg/kg50 days
ADA Scientific Sessions 2026 abstract5 Jun 2026
Fasting blood glucose
downin mice1−19%
1 study
Fasting blood glucose
downin mice1−19%
Inhbe sirna decreases fasting blood glucose in mice (-18.7%).
“FBG decreased by 18.7%.”
Animalsdiet-induced obesity9 mg/kg50 days
ADA Scientific Sessions 2026 abstract5 Jun 2026
Body weight
downin mice1−12%
1 study
Body weight
downin mice1−12%
Inhbe sirna decreases body weight in mice (-12.25%).
“Following the administration of INHBE-siRNA (9 mg/kg, weekly) for 50 days, DIO hINHBE mice showed a 12.25% reduction in body weight compared to baseline.”
Animalsdiet-induced obesity9 mg/kg50 days
ADA Scientific Sessions 2026 abstract5 Jun 2026
Latest
1 in 12 monthsADA Scientific Sessions 2026 Abstract
INHBE-siRNA as a Promising Antiobesity Therapy: Preclinical Evaluation in Diet-Induced-Obesity Humanized INHBE Mice
Experiments in miceObesity