Inhbe sirna

Intervention

1 paper3 findings

  • 1 lab
  • Animals1

Outcomes

3

INHBE mRNA

downin mice1−94%

1 study
  1. Inhbe sirna decreases INHBE mRNA in mice (-93.8%).

    “INHBE mRNA levels decreased by 93.8%.”

    Animalsdiet-induced obesity9 mg/kg50 days

    INHBE-siRNA as a Promising Antiobesity Therapy: Preclinical Evaluation in Diet-Induced-Obesity Humanized INHBE Mice

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on INHBE mRNA

Fasting blood glucose

downin mice1−19%

1 study
  1. Inhbe sirna decreases fasting blood glucose in mice (-18.7%).

    “FBG decreased by 18.7%.”

    Animalsdiet-induced obesity9 mg/kg50 days

    INHBE-siRNA as a Promising Antiobesity Therapy: Preclinical Evaluation in Diet-Induced-Obesity Humanized INHBE Mice

    ADA Scientific Sessions 2026 abstract5 Jun 2026

More on Fasting blood glucose

Body weight

downin mice1−12%

1 study
  1. Inhbe sirna decreases body weight in mice (-12.25%).

    “Following the administration of INHBE-siRNA (9 mg/kg, weekly) for 50 days, DIO hINHBE mice showed a 12.25% reduction in body weight compared to baseline.”

    Animalsdiet-induced obesity9 mg/kg50 days

    INHBE-siRNA as a Promising Antiobesity Therapy: Preclinical Evaluation in Diet-Induced-Obesity Humanized INHBE Mice

    ADA Scientific Sessions 2026 abstract5 Jun 2026

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