IL-7 complexes

Intervention

1 paper studies it2 findings

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 4 more
  • Animals1

Outcomes

2

Lifespan

no changein mice1

1 study
  1. IL-7 complexes have no effect on lifespan in mice.

    “This improved the numbers of NS4b-specific CD8 T cells detected at the peak of the response against WNV, but not survival of WNV challenge.”

    AnimalsWNV challenge

    Quantitative restoration of immune defense in old animals determined by naive antigen-specific CD8 T-cell numbers

    Aging cell

Total T cell count

upin mice1

1 study
  1. IL-7 complexes increase total T cell count in mice (>fourfold).

    “T cells underwent robust expansion following IL-7C administration to old mice increasing the number of total T cells (>fourfold)”

    Animals

    Quantitative restoration of immune defense in old animals determined by naive antigen-specific CD8 T-cell numbers

    Aging cell

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