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Hypothalamic stem/progenitor cell ablation

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Heart, Lung, and Blood Institute and 3 more
  • Animals1

Outcomes

1

Lifespan

downin mice1

1 study

  1. Hypothalamic stem/progenitor cell ablation shortens lifespan in mice.

    “Each mouse model consistently displayed acceleration of ageing-like physiological changes or a shortened lifespan.”

    Animalsablation of hypothalamic stem/progenitor cells co-expressing Sox2 and Bmi1

    Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

    Nature26 Jul 2017

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