Hypertrophy training

Hypertrophy training has been studied in 2 papers since 2024: 2 trials in people; 1 in the past year. The newest paper, Feb 12, 2026: “Load- and velocity-specific adaptations to lower-body maximal strength training (MST), hypertrophy training (HT) and explosive strength training (EST)”.

Intervention

2 papers study it2 findingsUpdated

See all 2 papers on hypertrophy training

At a glance

The findings reach people, from one lab or study. 2 independent labs in 2 countries.

“MST and HT improved squat 1RM (+ 20.7% and + 18.2%) more than EST (+ 10.9%) (all p ≤ 0.01) and CON (all p ≤ 0.001).”
Load- and velocity-specific adaptations to lower-body maximal strength training (MST), hypertrophy training (HT) and explosive strength training (EST)European journal of applied physiology2026doi:10.1007/s00421-026-06156-2

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 2 independent labs in 2 countries
  • Funder: Nord University
  • Human trial2

Studies in people

2 studies gave hypertrophy training to people and measured what changed.

What changedDesignPeopleSource

up: Improves squat 1RM strength+18.2%

Trial8 weeks58 peopleBothEuropean journal of applied physiology, Feb 12, 2026

up: Increases bone mineral density

Randomized trial12 months16 peopleWomen60 and 70 yearsOlder adultsJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, Aug 14, 2024

What did studies of hypertrophy training find?

2

Studies of hypertrophy training measured 2 outcomes: squat 1RM strength and bone mineral density.

Squat 1RM strength

upin humans1+18%

1 study
  1. Hypertrophy training improves squat 1RM strength in humans (+18.2%).

    “MST and HT improved squat 1RM (+ 20.7% and + 18.2%) more than EST (+ 10.9%) (all p ≤ 0.01) and CON (all p ≤ 0.001).”

    Human trial8 weeksn = 58

    Load- and velocity-specific adaptations to lower-body maximal strength training (MST), hypertrophy training (HT) and explosive strength training (EST)

    European journal of applied physiology

Bone mineral density

upin humans1

1 study
  1. Hypertrophy training increases bone mineral density in humans.

    “WB BMD and L1-L4 BMD increased in the hypertrophy training group, while TH BMD and FN BMD remained unchanged.”

    Human trialbone12 monthsfemalesn = 16

    Effects of Two Types of Resistance Training Modalities (Hypertrophy vs. Contrast Training) on Bone Parameters in a Group of Healthy Elderly Women

    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

More on Bone mineral density

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 1Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months