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Hypertonic stress

Hypertonic stress has been studied in 1 paper since 2016: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Feb 9, 2016: “C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins”.

Exposure

1 paper studies it1 findingUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Ellison Medical Foundation and 4 more
  • Model organisms1

What did studies of Hypertonic stress find?

1

Studies of Hypertonic stress measured 1 outcome; the most studied are lifespan (1 study).

Lifespan

downin worms1

1 study

  1. Hypertonic stress shortens lifespan in worms.

    “By contrast, in the absence of FUdR, hypertonic stress decreases lifespan.”

    Model organismsIn the absence of FUdR

    C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins

    Mechanisms of ageing and development

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