Human umbilical cord blood cells transduced with adeno-viral vectors encoding human gdnf and ncam

Human umbilical cord blood cells transduced with adeno-viral vectors encoding human gdnf and ncam improves behavioral performance in mice.

“Significant improvement in behavioral performance (open-field and grip-strength tests), as well as increased life-span was observed in rodents treated with NCAM-VEGF or NCAM-GDNF co-transfected cells”

Animalsin transgenic ALS mice

Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule

Current gene therapy·Jan 1, 2015

Human umbilical cord blood cells transduced with adeno-viral vectors encoding human gdnf and ncam extends lifespan in mice.

“increased life-span was observed in rodents treated with NCAM-VEGF or NCAM-GDNF co-transfected cells”

Animalsin transgenic ALS mice

Symptomatic improvement, increased life-span and sustained cell homing in amyotrophic lateral sclerosis after transplantation of human umbilical cord blood cells genetically modified with adeno-viral vectors expressing a neuro-protective factor and a neural cell adhesion molecule

Current gene therapy·Jan 1, 2015