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Human adipose tissue-derived pericytes

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Universidade de São Paulo
  • Animals1

Outcomes

2

Type I interferon signaling

downin mice1

1 study

  1. Human adipose tissue-derived pericytes inhibit type I interferon signaling in mice.

    “Microarray analysis showed an inhibition of the interferon pathway by adipose derived pericytes.”

    Animalsin double mutant Utrn (tm1Ked) Dmd (mdx) /J mice treated with adipose derived pericytes

    Human adipose tissue derived pericytes increase life span in Utrn (tm1Ked) Dmd (mdx) /J mice

    Stem cell reviews and reportsDec 1, 2014

More on Type I interferon signaling

Lifespan

upin mice1

1 study

  1. Human adipose tissue-derived pericytes extend lifespan in mice (39 days on average).

    “adipose tissue derived pericytes are able to increase significantly (39 days on average) the life span of affected mice”

    Animalsin double mutant Utrn (tm1Ked) Dmd (mdx) /J micehuman adipose tissue derived pericytes10(6) cells8 weeks

    Human adipose tissue derived pericytes increase life span in Utrn (tm1Ked) Dmd (mdx) /J mice

    Stem cell reviews and reportsDec 1, 2014

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