AgingResearch.NewsJoin free

Human adipose-derived stem cells engineered to secrete HYAL2-TARGETING sirnas

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Wrinkles

downin mice1

1 study

  1. Human adipose-derived stem cells engineered to secrete HYAL2-TARGETING sirnas decrease wrinkles in mice.

    “effectively smoothing deep wrinkles and improving skin appearance”

    Animalsaged mouse skinskin

    Protecting and rejuvenating ageing skin by regulating endogenous hyaluronan metabolism using adipose-derived stem cell-secreted siRNAs

    Frontiers in medicineApr 29, 2025

Photoaging

downin mice1

1 study

  1. Human adipose-derived stem cells engineered to secrete HYAL2-TARGETING sirnas protect against photoaging in mice.

    “significantly protects mouse skin from accelerated HA degradation, helping to retain water content and prevent UV-induced dryness”

    Animalsprior to UV exposuresubcutaneous implantationskin

    Protecting and rejuvenating ageing skin by regulating endogenous hyaluronan metabolism using adipose-derived stem cell-secreted siRNAs

    Frontiers in medicineApr 29, 2025

More on Photoaging

Latest

Related