Huan le ning decoction

1. Huan le ning decoction activates notch signalling in mice.

   Animalsnatural aging with chronic unpredictable mild stressdecoctionhippocampustwo weeksfemales

   Synaptic remodeling and functional recovery: Huan Le Ning decoction mitigates perimenopausal anxiety and depression symptoms via hippocampal reorganization · Journal of ethnopharmacology · 4 Sep 2026

Notch signalling →

1. Huan le ning decoction increases estrogens in mice.

   Animalsnatural aging with chronic unpredictable mild stressdecoctionserumtwo weeksfemales

   Synaptic remodeling and functional recovery: Huan Le Ning decoction mitigates perimenopausal anxiety and depression symptoms via hippocampal reorganization · Journal of ethnopharmacology · 4 Sep 2026

Estrogens →

1. Huan le ning decoction decreases depression in mice.

   Animalsnatural aging with chronic unpredictable mild stressdecoctiontwo weeksfemales

   Synaptic remodeling and functional recovery: Huan Le Ning decoction mitigates perimenopausal anxiety and depression symptoms via hippocampal reorganization · Journal of ethnopharmacology · 4 Sep 2026

Depression →

1. Huan le ning decoction decreases anxiety in mice.

   Animalsnatural aging with chronic unpredictable mild stressdecoctiontwo weeksfemales

   Synaptic remodeling and functional recovery: Huan Le Ning decoction mitigates perimenopausal anxiety and depression symptoms via hippocampal reorganization · Journal of ethnopharmacology · 4 Sep 2026

Anxiety →