Head-down bed rest

1. Head-down bed rest increases center of pressure mean velocity in humans (+ 20% [+ 8%; +46%], p < 0.001).

   “The mean velocity was increased on both axes (+ 20% [+ 8%; +46%] for medio-lateral and + 19% [+ 13%; +36%] for antero-posterior, both p < 0.001).”

   Human trialmedio-lateral axis14 daysn = 22

   Reduced postural stability in men and women aged 55-65 following 14 days of head-down bed rest

   Scientific reports·30 Oct 2025

More on Center of pressure mean velocity

1. Head-down bed rest increases center of pressure root mean square in humans (+53% [+ 15%; +129%], p = 0.002).

   “With eyes open, the root mean square of the center of pressure was larger immediately after HDBR only in the medio-lateral axis (median [interquartile range]: +53% [+ 15%; +129%], p = 0.002).”

   Human trialeyes open, medio-lateral axis14 daysn = 22

   Reduced postural stability in men and women aged 55-65 following 14 days of head-down bed rest

   Scientific reports·30 Oct 2025

More on Center of pressure root mean square

1. Head-down bed rest impairs postural stability in humans.

   “14-day HDBR decreased postural stability in individuals aged 55-65, with no impact of the chosen countermeasure.”

   Human trial14 daysn = 22

   Reduced postural stability in men and women aged 55-65 following 14 days of head-down bed rest

   Scientific reports·30 Oct 2025