Glucagon-like PEPTIDE-2

Intervention

1 paper3 findings

MeSH

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Oxidative stress and ROS signalling

downin mice1

1 study
  1. Glucagon-like PEPTIDE-2 decreases oxidative stress and ROS signalling in mice.

    “Furthermore, the oxidative stress in the intestines was improved by increasing the GPX-4 and SOD-2 signaling.”

    Animalssenile osteoporosis modelsubcutaneously injectedintestine6 weeksmales

    Glucagon-Like Peptide-2 Ameliorates Age-Associated Bone Loss and Gut Barrier Dysfunction in Senescence-Accelerated Mouse Prone 6 Mice

    GerontologyDec 5, 2022

More on Oxidative stress and ROS signalling

Inflammation

downin mice1

1 study
  1. Glucagon-like PEPTIDE-2 decreases inflammation in mice.

    “Moreover, GLP-2 ameliorated tight junction structure and protein expression in the intestinal barrier, which was accompanied by the reduction of TNF-α level.”

    Animalssenile osteoporosis modelsubcutaneously injectedintestine6 weeksmales

    Glucagon-Like Peptide-2 Ameliorates Age-Associated Bone Loss and Gut Barrier Dysfunction in Senescence-Accelerated Mouse Prone 6 Mice

    GerontologyDec 5, 2022

More on Inflammation

Bone loss

downin mice1

1 study
  1. Glucagon-like PEPTIDE-2 decreases bone loss in mice.

    “Six-week GLP-2 treatment attenuated bone loss in SAMP6 mice, as evidenced by increased bone mineral density, improved microarchitecture in femora, and enhanced osteogenic activities.”

    Animalssenile osteoporosis modelsubcutaneously injectedfemur6 weeksmales

    Glucagon-Like Peptide-2 Ameliorates Age-Associated Bone Loss and Gut Barrier Dysfunction in Senescence-Accelerated Mouse Prone 6 Mice

    GerontologyDec 5, 2022

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