Gestational protein restriction

1. Gestational protein restriction increases CD68-positive cell count in mice.

   “Immunohistochemical analysis demonstrated increased CD68+ cells in aged LP animals, indicating expansion of the skeletal myeloid compartment.”

   AnimalsOffspring of dams fed a low-protein dietlow-protein dietboneduring gestationmales

   Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging

   Calcified tissue international·24 Jul 2026

More on CD68-positive cell count

1. Gestational protein restriction increases cortical porosity in mice.

   “Ultrastructural analyses revealed increased cortical porosity and disrupted collagen fiber organization in aged LP bone.”

   AnimalsOffspring of dams fed a low-protein dietlow-protein dietcortical boneduring gestationmales

   Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging

   Calcified tissue international·24 Jul 2026

More on Cortical porosity

1. Gestational protein restriction decreases femoral maximal load in mice.

   “Three-point bending tests demonstrated reduced maximal load in LP-18 M femora, indicating compromised mechanical strength.”

   AnimalsOffspring of dams fed a low-protein diet versus a normal-protein dietlow-protein dietfemurduring gestationmales

   Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging

   Calcified tissue international·24 Jul 2026

More on Femoral maximal load

1. Gestational protein restriction decreases cortical thickness in mice.

   “along with reduced cortical thickness at both ages.”

   AnimalsOffspring of dams fed a low-protein diet versus a normal-protein dietlow-protein dietcortical boneduring gestationmales

   Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging

   Calcified tissue international·24 Jul 2026

More on Cortical thickness

1. Gestational protein restriction decreases bone mineral density in mice.

   “Microcomputed tomography revealed significant reductions in trabecular bone volume fraction, bone mineral density, and trabecular number in 18-month-old LP offspring”

   AnimalsOffspring of dams fed a low-protein diet versus a normal-protein dietlow-protein dietboneduring gestationmales

   Gestational Protein Restriction Promotes Osteoporotic Phenotype During Aging

   Calcified tissue international·24 Jul 2026

More on Bone mineral density