bioRxiv
Heavier male mice had larger lifespan gains from interventions
For weight-lowering interventions, median lifespan gains over controls rose from 6.2% in the lightest quarter of males to 20.2% in the heaviest.For weight-lowering interventions, median lifespan gains over controls rose from 6.2% in the lightest quarter of males to 20.2% in the heaviest.
Preprint: mouse study · 33,780 miceInterventions
Who was studied33,780 mice allowed to eat freely, against male mice in lightest weight quartile
What changedWith weight-lowering interventions, male mice's median lifespan gains over controls rose from 6.2% in the lightest quarter to 20.2% in the heaviest
The catchPoor control health could inflate apparent lifespan benefits in heavier mice