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Gelsenicine

Intervention

1 paper studies it4 findings

PubChemMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Fujian Provincial Health Technology Project and 2 more
  • Model organisms1

Outcomes

4

Oxidative stress and ROS signaling

upin worms1

1 study

  1. Gelsenicine induces oxidative stress and ROS signaling in worms.

    “Intestinal lipofuscin and ROS were increased”

    Model organismsintestine

    Gelsenicine disrupted the intestinal barrier of Caenorhabditis elegans

    Chemico-biological interactions

More on Oxidative stress and ROS signaling

Locomotion behavior

downin worms1

1 study

  1. Gelsenicine impairs locomotion behavior in worms.

    “reductions in body length, width, and locomotion behavior.”

    Model organisms

    Gelsenicine disrupted the intestinal barrier of Caenorhabditis elegans

    Chemico-biological interactions

Intestinal permeability

upin worms1

1 study

  1. Gelsenicine increases intestinal permeability in worms.

    “treatment of gelsenicine resulted in the increase of nematode intestinal permeability.”

    Model organismsintestine

    Gelsenicine disrupted the intestinal barrier of Caenorhabditis elegans

    Chemico-biological interactions

Lifespan

downin worms1

1 study

  1. Gelsenicine shortens lifespan in worms.

    “the treatment of gelsenicine resulted in the inhibition of nematode lifespan”

    Model organisms

    Gelsenicine disrupted the intestinal barrier of Caenorhabditis elegans

    Chemico-biological interactions

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