Fullerene C60
- 2 independent labs in 2 countries
- Animals2
Outcomes
2Lifespan
upin mice1upin rats1
2 studies
Lifespan
upin mice1upin rats1
Fullerene C60 extends lifespan in mice.
“Treatment of mice with C60 fullerenes resulted in an increased lifespan of males and females compared with the olive oil-treated animals.”
Animalsdissolved in virgin olive oil, compared with olive oil-treated animalsdissolved in virgin olive oil7 months
Effect of Long-Term Treatment with C₆₀ Fullerenes on the Lifespan and Health Status of CBA/Ca Mice
Rejuvenation researchMay 19, 2021
Fullerene C60 extends lifespan in rats (almost doubles).
“oral administration of C(60) dissolved in olive oil (0.8 mg/ml) at reiterated doses (1.7 mg/kg of body weight) to rats not only does not entail chronic toxicity but it almost doubles their lifespan”
Animalsdissolved in olive oil (0.8 mg/ml)1.7 mg/kg
The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene
BiomaterialsApr 10, 2012
Oxidative stress and ROS signaling
downin rats1
1 study
Oxidative stress and ROS signaling
downin rats1
Fullerene C60 decreases oxidative stress and ROS signaling in rats.
“effects of C(60)-olive oil solutions in an experimental model of CCl(4) intoxication in rat strongly suggest that the effect on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress”
Animalsexperimental model of CCl(4) intoxicationdissolved in olive oil
The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene
BiomaterialsApr 10, 2012