Expanded NMN-based nutritional formulation

Expanded NMN-based nutritional formulation has been studied in 1 paper since 2026: 1 trial in people; 1 in the past year. The newest paper, Oct 23, 2026: “Unlocking the Healthy Aging Potential of Novel NMN-Based Nutritional Formulations: Cardiopulmonary, Cognitive, and Aging-Related Outcomes in a 42-Day Open-Label Study”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1

“Exploratory biomarker analyses identified nominal between-group differences in CTACK (p = 0.015) and GDF-15 (p = 0.022), without adjustment for multiple testing”
Unlocking the Healthy Aging Potential of Novel NMN-Based Nutritional Formulations: Cardiopulmonary, Cognitive, and Aging-Related Outcomes in a 42-Day Open-Label StudyNutrients2026doi:10.3390/nu18213490

None of its findings points the other way.

  • 1 lab in 1 country
  • Funder: Abe Yoando Pharma
  • Human trial1

Studies in people

1 study gave expanded NMN-based nutritional formulation to people and measured what changed.

  • down: Decreases model-derived functional-age composite−2.79 years versus −0.63 years with placebo

    Trial40 people45–65 years42 days

    Midlife adults; Older adults; Exploratory placebo-versus-expanded-formulation subset

    Nutrients, Oct 23, 2026

What did studies of Expanded NMN-based nutritional formulation find?

1

Studies of Expanded NMN-based nutritional formulation measured 1 outcome; the most studied are model-derived functional-age composite (1 study).

Model-derived functional-age composite

downin humans1

1 study
  1. Expanded NMN-based nutritional formulation decreases model-derived functional-age composite in humans (Exploratory placebo-versus-expanded-formulation subset) (−2.79 years versus −0.63 years with placebo).

    “A model-derived functional-age composite decreased by 2.79 years in the expanded-formulation group compared with 0.63 years in placebo.”

    Human trialExploratory placebo-versus-expanded-formulation subseteight-component formulation42 days

    Unlocking the Healthy Aging Potential of Novel NMN-Based Nutritional Formulations: Cardiopulmonary, Cognitive, and Aging-Related Outcomes in a 42-Day Open-Label Study

    Nutrients

More on Model-derived functional-age composite

What is Expanded NMN-based nutritional formulation linked with?

1

Studies link Expanded NMN-based nutritional formulation with 1 measure, most often CTACK and GDF-15 (1 study).

CTACK and GDF-15

mixedin humans1

1 study
  1. Expanded NMN-based nutritional formulation is associated with CTACK and GDF-15 in humans (Exploratory placebo-versus-expanded-formulation subset; no adjustment for multiple testing) (CTACK p = 0.015; GDF-15 p = 0.022; directions not reported).

    “Exploratory biomarker analyses identified nominal between-group differences in CTACK (p = 0.015) and GDF-15 (p = 0.022), without adjustment for multiple testing”

    Human trialExploratory placebo-versus-expanded-formulation subset; no adjustment for multiple testingeight-component formulation42 days

    Unlocking the Healthy Aging Potential of Novel NMN-Based Nutritional Formulations: Cardiopulmonary, Cognitive, and Aging-Related Outcomes in a 42-Day Open-Label Study

    Nutrients

More on CTACK and GDF-15

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