EPHX2 inhibitors
Intervention1 paper1 finding
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.
- Humans1
Outcomes
1Cognitive function
upin mice1
1 study
Cognitive function
upin mice1
EPHX2 inhibitors improve cognitive function in mice.
Animals5xFAD mouse model of Alzheimer's disease
Genetic data highlight potential drug targets for Alzheimer's · Nature neuroscience · 8 Oct 2026
Latest
1Genetic data highlight potential drug targets for Alzheimer's
A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.