Baclofen
Intervention1 paper1 findingPubChem 2284ChEBI 2972
C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
Against: findings that point the other way from most findings on the same outcome.
No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.
Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.
- Humans1
Associations
1Alzheimer's disease incidence
downin humans1
1 study
Alzheimer's disease incidence
downin humans1
Baclofen is associated with alzheimer's disease incidence in humans.
Humanspatients with mild cognitive impairmentn = 111,680
Genetic data highlight potential drug targets for Alzheimer's · Nature neuroscience · 8 Oct 2026
Latest
1Genetic data highlight potential drug targets for Alzheimer's
A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.A Mendelian randomisation analysis identified 19 candidate targets in people of European ancestry and seven in people of African ancestry.